Close-up of an eye with a ring-shaped light reflection on the cornea.

Expertise

Keratoconus

Keratoconus is a disease in which the cornea gradually thins and takes on a cone shape; vision becomes blurred and cannot be fully corrected with glasses. This page explains how the disease is assessed and by what logic treatment options are chosen.

Definition

What is keratoconus?

The cornea is the transparent, dome-shaped layer at the front of the eye and is among the principal structures that focus light. In keratoconus this layer thins and gradually takes on a cone shape. When the dome loses its regular form, light can no longer be gathered at a single point on the retina; the result is blurred, distorted vision that glasses do not fully correct.

The disease is usually noticed in adolescence and young adulthood and most often affects both eyes, although the change may differ between the two eyes. Its course varies from person to person: in some eyes it stays stable for years, in others it can progress.

For this reason, diagnosis rests not on a single measurement but on a comprehensive examination carried out together with corneal mapping. The treatment decision, too, is made with the physician according to this assessment and the course of the disease.

When it begins
Usually noticed in adolescence and young adulthood.
Symptoms
Blurred or distorted vision, a frequently changing glasses prescription, light sensitivity, halos and glare around lights.
Risk factors
A family history of keratoconus, an allergic (atopic) constitution, frequent and vigorous eye rubbing.

Assessment

How is it assessed?

When keratoconus is suspected, the examination proceeds with measurements that are painless and mostly do not require touching the eye. The following are the main steps you may encounter in the examination; which of them are needed varies from person to person.

  1. Topography and tomography

    It produces a map of the corneal surface. You rest your chin on the device and look at the light in the center; a few measurements are taken. Steepening and irregularity on the map are the main data in assessing corneal shape.

  2. Pachymetry

    This is the measurement of corneal thickness. The thickness map is used in deciding which treatments may be suitable. With some measurement methods the eye may be numbed with drops.

  3. Biomechanical measurements

    These are measurements that give additional information about the elasticity of the cornea; they support the diagnosis and are interpreted at follow-up. The device may also work by blowing a gentle puff of air in front of the eye.

The measurements are interpreted together; no single value establishes the diagnosis. If progression is suspected, the same measurements are repeated at set intervals and compared with one another. The physician determines the follow-up schedule.

Treatment

Treatment options

Depending on the physician's assessment, the following options may be considered singly or together. Which one is suitable depends on the stage of the disease, the corneal thickness and whether the disease is progressing.

  1. Corneal cross-linking (CXL)

    Riboflavin (vitamin B2) is dropped onto the cornea and ultraviolet A light is applied at a controlled dose; the aim is to slow or halt progression by allowing new bonds to form in the corneal tissue. It does not aim to correct vision. According to the physician's assessment, it is considered in eyes where progression has been identified.

  2. Intracorneal ring

    Thin, partial ring segments are placed inside the cornea; the aim is to reshape the cornea and so reduce part of the astigmatism and myopia. According to the physician's assessment, it is considered in eyes whose corneal thickness and stage of disease are suitable.

  3. Topography-guided surface ablation and cross-linking

    A thin surface correction planned from the corneal map may be applied together with cross-linking. The aim is to reduce part of the surface irregularity while strengthening the cornea. According to the physician's assessment, it is considered in selected eyes.

  4. Special contact lenses

    Special designs such as rigid gas-permeable, scleral and hybrid lenses can give clearer vision than glasses on an irregular corneal surface. Lens selection and fit are determined by examination; the need for lenses may continue after cross-linking.

  5. Keratoplasty in advanced disease (DALK)

    This is a deep anterior lamellar corneal transplant in which the front layers of the cornea are replaced with donor tissue. According to the physician's assessment, it is considered if the disease is advanced or if lenses cannot provide sufficient vision.

Results may vary from person to person in any surgical or interventional procedure. This page is for information only; the treatment decision is made together with the physician after examination.

Questions

Frequently asked questions

Is cross-linking painful?

During the procedure the eye is numbed with drops. In the first days burning, stinging, watering and light sensitivity may occur; the severity varies from person to person. The physician gives the necessary drops and care recommendations.

From what age is it performed?

Age alone is not decisive. In keratoconus that is progressing it can also be considered in children and young people; the physician decides according to the examination findings.

Can I keep wearing lenses?

Lens wear is paused during the healing period after the procedure; the physician determines when it can be resumed. The need for special lenses may continue after the procedure.

Do glasses or lenses correct keratoconus?

Glasses and lenses do not treat the disease; they support vision. In the early stage glasses may be sufficient; as corneal irregularity increases, special lenses may be needed. Progression of the disease is assessed separately.

Is rubbing the eyes harmful?

Frequent and vigorous eye rubbing is one of the known risk factors for keratoconus. If there is itching, its cause, for example eye allergy, is investigated together with the physician.

Does keratoconus lead to loss of vision?

It is a disease that can be monitored when followed regularly; in eyes that progress, the quality of vision may decline. In advanced cases a corneal transplant may be considered. It is therefore important not to miss check-ups.

Record

Publications on this subject

Six of Prof. Dr. Yusuf Yıldırım's studies on keratoconus, ordered by number of citations.

All publications
  1. 2012

    Accelerated corneal crosslinking concurrent with laser in situ keratomileusis

    Journal of Cataract & Refractive Surgery · 38(8):1424

    115 citations

    DOI (opens in a new tab)
  2. 2015

    Accelerated Corneal Collagen Cross-Linking in Thin Keratoconic Corneas

    Journal of Refractive Surgery · 31(6):386

    53 citations

    DOI (opens in a new tab)
  3. 2014

    Evaluation of Corneal Stromal Demarcation Line after Two Different Protocols of Accelerated Corneal Collagen Cross-Linking Procedures Using Anterior Segment Optical Coherence Tomography and Confocal Microscopy

    Journal of Ophthalmology · 2014

    40 citations

    DOI (opens in a new tab)
  4. 2019

    Different accelerated corneal collagen cross-linking treatment modalities in progressive keratoconus

    Eye and Vision · 6(1):16

    39 citations

    DOI (opens in a new tab)
  5. 2020

    Complications of accelerated corneal collagen cross-linking: review of 2025 eyes

    International Ophthalmology · 40(12):3269

    32 citations

    DOI (opens in a new tab)
  6. 2017

    Comparison of Accelerated Corneal Collagen Cross-linking Types for Treating Keratoconus

    Current Eye Research · 42(7):971

    28 citations

    DOI (opens in a new tab)

Data are taken from OpenAlex and Web of Science; last updated October 14, 2026.